Urinary Excretion of Alanine Aminopeptidase and N-Acetyl-β-D-Glucosaminidase During Sequential Combination Chemotherapy
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منابع مشابه
Excretion of urinary N-acetyl-beta-D-glucosaminidase isoenzymes after renal transplantation in the rat.
The urinary excretion of N-acetyl-beta-D-glucosaminidase isoenzymes A and B following kidney transplantation was studied in rats. High enzymuria with permanent marked isoenzyme B excretion occurred from the immediate post-operative period to the irreversible rejection episode. Isoenzyme B could represent as much as 10-40% of total N-acetyl-beta-D-glucosaminidase activity and it reflected the in...
متن کاملIs urinary N-acetyl-beta-D-glucosaminidase a marker of urological abnormality in children?
Abstract Background: Hydronephrosis is the most common congenital condition that is detected by prenatal ultrasonography. Moreover, the widespread use of prenatal ultrasonography results in an increased recognition of fetal hydronephrosis. Prenatal hydronephrosis is diagnosed at an incidence of 1:100 to 1:500 by ultrasonographic studies. The presence of hydronephrosis is not synonymou...
متن کاملUrinary N-Acetyl-β-D-Glucosaminidase Excretion in Asphyctic Newborns-Does it Predict the Development of Acute Renal Failure?
Perinatal asphyxia is the major cause of acute renal failure (ARF) in neonates. The renal proximal tubules have a high metabolic activity and are extremely sensitive to hypoxia (1,2). Renal function deteriorates in a spectrum from mild tubular dysfunction to acute tubular necrosis depending on the severity of hpoxic insult. It is essential to evaluate renal function at an early stage to stabili...
متن کاملUrinary biomarker N-acetyl-β-D-glucosaminidase can predict severity of renal damage in diabetic nephropathy
BACKGROUND Diabetic nephropathy is a clinical diagnosis where proteinuria is present in a patient with diabetes. Early intervention can significantly improve the prognosis. However, imprecision of the currently available biomarkers have impaired effective therapies in a timely manner. Urinary N-acetyl-β-D-glucosaminidase (NAG) is excreted in abnormally high amounts in many renal diseases. The a...
متن کاملUrinary Activities of N-acetyl-β-D-glucosaminidase and Its Isoenzyme B in Cadmium-Exposed Rats
This paper aims to assess the relationship between the urinary activity of N-acetyl-β-D-glucosaminidase (NAG) and its isoenzyme B (NAG-B) and cadmium (Cd) concentration in the urine as well as to evaluate which of these lysosomal enzymes may be a more useful biomarker for the monitoring of Cd-induced tubular damage. For this purpose we have used an experimental model in rats chronically exposed...
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine
سال: 1982
ISSN: 1434-6621,1437-4331
DOI: 10.1515/cclm.1982.20.9.615